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The Genetics of Hereditary Colon and Rectal Cancer
Part 4: Familial Adenomatous Polyposis: One Gene, Many Manifestations ISSUE: AUGUST, 2010 In Part 4 of this series on Hereditary Colorectal Cancer, the authors examine how to diagnose and treat patients and family members affected by familial adenomatous polyposis. read more (1 comments) | |
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Inherited Colon and Rectal Cancer: Surgical Perspectives
Part 3—Familial Adenomatous Polyposis and the Polyposis Syndromes: One Gene, Many Manifestations ISSUE: JULY, 2010 In Part 3, we examine familial adenomatous polyposis (FAP), other polyposis syndromes and the damage caused by these inherited diseases. Emphasis is placed on the genetics of the disease and how knowledge of the mutational pattern can help the clinician secure a diagnosis, and begin treatment. Look-alike diseases, those looking like FAP but arising from a mutation on a different gene, also will be considered. read more | |
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Inherited Colon and Rectal Cancer: Surgical Perspectives
Part 2: Hereditary Nonpolyposis Colorectal Cancer: From Diagnosis to Treatment ISSUE: JUNE, 2010 In this four-part series, Part 1 reviewed the basic pathologic and genetic concepts underlying hereditary nonpolyposis colorectal cancer. This second part defines the clinical challenges facing the clinician who is at the forefront of diagnostic and treatment efforts. read more | |
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Inherited Colon and Rectal Cancer: Surgical Perspectives
Part 1—Hereditary Nonpolyposis Colorectal Cancer: Genetics and Diagnosis ISSUE: MAY, 2010 By Jordan R.H. Hoffman and Gary H. Hoffman, MD With a myriad of vexing abbreviations and obscure terminology, the genetics controlling the formation of colonic polyps and malignancies may be difficult to appreciate. Paradoxically, the physician, positioned at the beginning of the diagnostic effort, is often the person most hampered by a lack of basic understanding of this genetic alphabet soup. read more |
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The Genetics of Hereditary Colon and Rectal Cancer  1 |
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